Xylocream Lidocaine Plus Prilocaine Cream is a topical local anesthetic cream containing lidocaine and prilocaine. It is used to temporarily numb the skin before minor medical or cosmetic procedures when recommended by a doctor or pharmacist. Lidocaine and prilocaine belong to the local anesthetic medicine group and work by blocking pain signals from the nerves in the applied area. This cream may be used before procedures such as needle insertion, blood sampling, minor skin procedures, laser treatment, or other superficial procedures as advised by a healthcare professional. It is for external use only and should be applied only to the area being treated, using the recommended amount and application time. Possible side effects may include temporary redness, paleness, swelling, itching, burning, tingling, irritation, or changes in skin sensation at the application site. These are not all the possible side effects. Talk to your healthcare provider if any side effect bothers you, becomes severe, or does not go away.