3M Nexcare Cold Hot Mini Reusable Therapy Pack For Pain Relief can be used cold or hot and is an solution for those who prefer natural, drug-free therapy. It can be cooled in the freezer or refrigerator or be heated in hot water or in microwave. Protective cover for the gel pack is included allowing quick/easy and comfortable application ensuring furthermore safety for your skin. Use cold for tooth ache, acute injuries (bruises, sprains, minor bumps), fever (not intended to decrease body temperature), nosebleeds, post injection and insect bites swelling. Use heated for sinus inflammation, wrist arthritis/rheumatoid arthritis or hand warming.