Fexodine 120 mg Tablets contains fexofenadine hydrochloride, which is an antihistamine. Fexodine 120 mg is used in adults and adolescents of 12 years and older Fexofenadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.