Loratin Tablet Contains loratadine which is a non-sedating, long-acting second-generation H1-receptor antagonist that has anti-allergic effect. Loratin does not appear to cross the blood brain barrier to a significant extent. Therefore, Loratin does not generally cause sedation or anticholinergic effects. Loratin tablets are designed to contain micronised loratadine; which has a high rate of absorption that is enhanced by food ingestion. Unlike other anti-histamines, Loratin does not lose its efficacy over long term use.